Table 2.
Classification of SMA.
SMA Type | Age of Onset | Maximum Age of Survival | SMN2 Copy Number | Alternate Name |
---|---|---|---|---|
0 | Prenatal | <1 month | 1 | - |
1 | 0–6 months | <2 years | 2 | Werdnig–Hoffman disease |
2 | <18 months | >2 years | 3,4 | Dubowitz disease |
3a (juvenile onset) | 18 months–3 years | Adult | 3,4 | Kugelberg–Welander disease |
3b | >3 years | Adult | 4 | Kugelberg–Welander disease |
4 | > 21 years | Adult | 4–8 | - |