Diagnosis of inoperable MCTs |
Dogs with findings suggestive of cardiac, kidney, or liver diseases |
MCTs localized in sites not amenable to surgical resection |
Concomitant neoplasms |
Eligibility to receive chemotherapy with IM or VP |
Concurrent diseases requiring immunosuppressive therapy (i.e., severe atopic or immune-mediated disease) other than prednisone |
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Concurrent systemic antineoplastic therapy |
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MCTs with systemic spread |
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Involvement of more than one lymph node |
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Dogs weighing less than 5 kg or intended for breeding |