Table 5.
Target lesion response.
| Treatment Group/Target Lesion Response * | IM Number of Dogs/Total (%) | VP Number of Dogs/ Total (%) |
|---|---|---|
| Partial response (PR) | 3/13 (23.07%) | 1/11 (9.09%) |
| Complete response (CR) | 1/13 (7.69%) | none |
| Stable disease (SD) | 5/13 (38.46%) | 6/11 (54.54%) |
| Progressive disease (PD) | 4/13 (30.80%) | 4/11 (36.36%) |
| Objective response rate (ORR)(PR + CR) | 4/13 (30.76%) * | 1/11 (9.09%) |
* According to VCOG [21] Stable disease (SD): less than 30% reduction (PR) or 20% increase (PD) in the sum of diameters of target lesions, taking as a reference the smallest sum of diameters in the study; partial response (PR): at least a 30% reduction in the sum of diameters of target lesions, taking as a reference the baseline sum; progressive disease (PD): either the appearance of one or more new lesions or at least a 20% increase in the sum of diameters of target lesions, taking as a reference the smallest sum on study. The total also showed an absolute increase of 5 mm. Complete response (CR): disappearance of all target lesions. Pathologic LNs. * p = 0.0003 when compared to VP.