Table 1.

Pros and cons of the three methods for exosome isolation [74].

Method	Pros	Cons
Ultracentrifugation	Low cost, high purity, massive production	Time-consuming, mechanical damage, specialized equipment requirement
Ultrafiltration	Low cost, less time consuming, good portability	Moderate purity, mechanical damage, high cost
Immunological separation	High purity, no chemical contamination, simple	Small volume production, high cost