Table 4.
Analysis of sensitivity of cost categories to different scenarios for nasopharynx cancer (NPC) and sinonasal cancer (SNC).
| Assumptions | Range | NPC a | Change | SNC b | Change |
|---|---|---|---|---|---|
| Healthcare costs (pre-diagnosis; initial phases) | CAD 32,659; CAD 55,761 | CAD 5.28 M | −2.9% | CAD 6.72 M | −0.4% |
| CAD 36,283; CAD 60,630 | CAD 5.46 M | 0.5% | CAD 6.77 M | 0.4% | |
| Out-of-pocket costs (per month) | CAD 400 | CAD 5.20 M | −4.2% | CAD 6.52 M | −3.4% |
| CAD 600 | CAD 5.90 M | 8.6% | CAD 7.20 M | 6.8% | |
| Informal caregiving wage (per hours) | CAD 6 | CAD 5.34 M | −1.8% | CAD 6.65 M | −1.4% |
| CAD 13 | CAD 5.54 M | 1.9% | CAD 6.84 M | 1.5% | |
| Recurrence rate | 12% | CAD 5.41 M | −0.5% | CAD 6.65 M | −1.4% |
| 22% | CAD 5.46 M | 0.5% | CAD 6.84 M | 1.5% | |
| Fringe benefit | 10% | CAD 5.34 M | −1.8% | CAD 6.65 M | −1.4% |
| 20% | CAD 5.58 M | 2.7% | CAD 6.88 M | 2.1% | |
| Productivity growth | 0.5% | CAD 5.38 M | −1.0% | CAD 6.69 M | −0.8% |
| 2% | CAD 5.55 M | 2.1% | CAD 6.85 M | 1.6% | |
| Monetary value per QALY c | CAD 100,000 | CAD 6.77 M | 24.6% | CAD 8.14 M | 20.7% |
| CAD 150,000 | CAD 8.10 M | 49.1% | CAD 10.26 M | 52.1% | |
| Cases (Cl of 95%) d | NPC:9; SNC:6 | CAD 4.22 M | −22.4% | CAD 3.82 M | −43.3% |
| NPC:29; SNC:32 | CAD 14.51 M | 167.0% | CAD 19.98 M | 196.3% |
Notes. a Total economic burden of nasopharynx cancer, b Total economic burden of sinonasal cancer, c assumeing different monetary values for a Quality-Adjusted Life-Years. d lower and higher bound of the expected cancer cases with confidence intervenal of 95%. Owing to rounding columns and rows may not sum. All monetary values are in 2011 Canadian dollars and M denotes that the units of figures presented are in millions.