Table 2.
miRNA | Expression | Sample | Sample Size | Diagnostic Implication | Ref. No. |
---|---|---|---|---|---|
miR-193b | ⬆ | Serum, FFPE | 37 | Healthy vs PanNETs | [121] |
miR-103 miR-107 |
⬆ | FFPE | 96 | Healthy vs. tumor | [116] |
miR-155 | ⬇ | ||||
miR-99a, 99b, 100, 125a, 125b-1, 125b-2, 129-2, 130a, 132, 342 | ⬆ | PanNETs vs. pancreatic adenocarcinoma/normal pancreas | |||
miR-451a, 372-3p, 106a-5p, 17-5p, 25-3p, 644a | ⬆ | Serum, FFPE | 140 | PanNETs vs. chronic pancreatitis | [130] |
miR-22-3p, 1246, 4454, 7975, 320e | ⬇ | ||||
miR-451a, 26b-5p, 25-3p, 16-5p | ⬆ | PanNETs vs. pancreatic adenocarcinoma | |||
miR-1322, 1285-5p, 320e | ⬇ | ||||
miR-24, 30a-3p, 18a, 92a, 342-3p, 99b, 106b, 142-3p, 532-3p | N/A | FFPE | 120 | High-grade IPMNs, cystic PanNETs, and SPN vs. low-grade IPMN, SCA | [110] |
miR-615 and -92b miR-429 and -487b | N/A | FFPE | 81 | PanNETs vs. ileal, appendicular, rectal neuroendocrine tumors | [133] |
IPNM, intraductal papillary mucinous neoplasms; SPN, solid pseudopapillary neoplasms; SCA, serous cystadenomas; FFPE, formalin-fixed paraffin-embedded tissue.