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. 2022 Jan 20;23(3):1109. doi: 10.3390/ijms23031109

Table 2.

The diagnostic role of miRNAs in PanNETs.

miRNA Expression Sample Sample Size Diagnostic Implication Ref. No.
miR-193b Serum, FFPE 37 Healthy vs PanNETs [121]
miR-103
miR-107
FFPE 96 Healthy vs. tumor [116]
miR-155
miR-99a, 99b, 100, 125a, 125b-1, 125b-2, 129-2, 130a, 132, 342 PanNETs vs. pancreatic adenocarcinoma/normal pancreas
miR-451a, 372-3p, 106a-5p, 17-5p, 25-3p, 644a Serum, FFPE 140 PanNETs vs. chronic pancreatitis [130]
miR-22-3p, 1246, 4454, 7975, 320e
miR-451a, 26b-5p, 25-3p, 16-5p PanNETs vs. pancreatic adenocarcinoma
miR-1322, 1285-5p, 320e
miR-24, 30a-3p, 18a, 92a, 342-3p, 99b, 106b, 142-3p, 532-3p N/A FFPE 120 High-grade IPMNs, cystic PanNETs, and SPN vs. low-grade IPMN, SCA [110]
miR-615 and -92b miR-429 and -487b N/A FFPE 81 PanNETs vs. ileal, appendicular, rectal neuroendocrine tumors [133]

IPNM, intraductal papillary mucinous neoplasms; SPN, solid pseudopapillary neoplasms; SCA, serous cystadenomas; FFPE, formalin-fixed paraffin-embedded tissue.