Figure 2.
The decrease in miR-150-5p expression in cultured macrophages is mediated by macrophage-derived exosomes. (A), exogenous administration of macrophage-derived exosomes for different periods of time. The macrophage-derived exosomes were extracted from macrophages under 25 mM glucose treatment for 1 h. (B), Quantitative real-time PCR of cytoplasmic miR-150-5p mRNA levels. Scramble siRNA was the control siRNA. The macrophage-derived exosomes were extracted from macrophages under 25 mM glucose treatment for 1 h. * p < 0.01 vs. control. ** p < 0.05 vs. control. n = 4 per group.