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. 2022 Jan 20;23(3):1095. doi: 10.3390/ijms23031095

Figure 6.

Figure 6

Macrophage-derived exosomal MALAT1-mediates the reduction of miR-150-5p expression after carotid artery balloon injury in diabetic rats. (A), Quantitative real-time PCR analysis of miR-150-5p levels in arterial tissue at 14 days after carotid artery balloon injury in diabetic rats. The macrophage-derived exosomes were extracted from macrophages under 25 mM glucose treatment for 1 h. Scramble siRNA was the control siRNA. (B), Quantitative real-time PCR of resistin mRNA levels in arterial tissue at 14 days after carotid artery balloon injury in diabetic rats. The macrophage-derived exosome was extracted from macrophages under 25 mM glucose treatment for 1 h. Scramble LNA GapmeR is a control siRNA. (C), Representative Western blots for resistin and α-tubulin protein levels in arterial tissues at 14 days after carotid artery balloon injury in diabetic rats. (D), Quantitative analysis of resistin protein levels. Scramble LNA GapmeR was the control siRNA. * p < 0.01 vs. control. n = 5 per group.