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. 2022 Feb 8;19(3):1873. doi: 10.3390/ijerph19031873

Table 3.

Effect of 17-β Estradiol (E2) and Parabens on the Expression of Selected Genes in MCF-7 and MCF-10A [57].

MCF-7
Genes CCND1 CCND3 CCNE1 CCNE2 CCNA2 CDK2 CDK4 CDK6 CDKN1A ATR ATM E2F3 TP53
E2 NC NC
MP NC NC NC NC NC NC NC NC NC
PP NC NC NC NC NC NC NC
BP NC NC NC NC NC NC
MCF-10A
Genes CCND1 CCND3 CCNE1 CCNE2 CCNA2 CDK2 CDK4 CDK6 CDKN1A ATR ATM E2F3 TP53
E2 NC NC NC NC NC
MP NC NC NC NC NC
PP NC NC NC
BP NC

MCF-7 and MCF-10A cells were exposed to MP, BP, and PP (20 nM) or E2 (10 nM) for 24 hours. Up arrow: Upregulation of gene expression; down arrow: Downregulation of gene expression; NC: Non change.