Skip to main content
. 2022 Jan 19;23(3):1083. doi: 10.3390/ijms23031083

Figure 3.

Figure 3

Reduction of endotoxin-aggravated mechanical ventilation-mediated mitochondrial dynamics in HIF-1α-deficient mice. Western blots were performed using antibodies that recognize Drp1 (A), Mfn2 (B), and GAPDH expression from the diaphragms of nonventilated control mice and mice ventilated at a tidal volume of 10 mL/kg for 8 h with or without LPS administration (n = 5 per group). Arbitrary units were expressed as relative Drp1 and Mfn2 activation (n = 5 per group). * p < 0.05 versus the nonventilated control mice with LPS treatment; † p < 0.05 versus all other groups. Drp1 = dynamin-related protein 1; Mfn2 = mitofusion 2.