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. 2022 Jan 28;15:737993. doi: 10.3389/fnins.2021.737993

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Copyright © 2022 Wei, Zhang, Li, Liu, Zha, Hu, Wang, Wang, Yu, Yang and Qiu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Clustering analysis of four states in chronic tinnitus patients before and after acupuncture. (A) Four states (centroids) from clustering analysis. The total number (in brackets) and proportion of occurrences are listed above each state. (B) Elbow criterion. The arrow represents the optimal k value. k, the number of clusters; Cluster validity index, calculating as the ratio of within-cluster distance to between-cluster distance. (C) Comparison of TP within chronic tinnitus patients before and after acupuncture. FR, other regions of frontal lobe; PR, parietal regions; OR, occipital regions; PFR, prefrontal regions; SUB, subcortex regions; TP, transition probability; TR, temporal regions. *P < 0.05.