Table 2.

Spearman’s correlations (r_S) between cell populations.

	ICU admission		Last determination
	r S	p-value	r S	p-value
G-MDSCs vs. M-MDSCs	0.296	0.0071*	0.326	0.0028*
vs. CD4+PD-1+OX40− T cells	0.140	0.2113	0.526	0.0004*
vs. CD8+PD-1+OX40− T cells	0.293	0.0081*	0.377	0.0014*
vs. total PD-1+OX40− T cells	0.261	0.0184*	0.473	0.0009*
vs. Tregs	-0.013	0.9071	-0.323	0.0030*
Total MDSCs vs. CD4+PD-1+OX40− T cells	0.088	0.4332	0.246	0.0271*
vs. CD8+PD-1+OX40− T cells	0.126	0.2624	0.280	0.0114*
vs. total PD-1+OX40− T cells	0.131	0.2453	0.296	0.0072*
CD4+PD-1+OX40− T cells vs. CD8+PD-1+OX40− T cells	0.340	0.0021*	0.579	0.0001*
CD4+OX40+PD-1− T cells vs. CD8+OX40+PD-1− T cells	0.255	0.0223*	0.536	0.0002*
Tregs vs. CD4+OX40+PD-1− T cells	0.504	0.0002*	0.516	0.0003*
vs. CD8+OX40+PD-1− T cells	0.285	0.0103*	0.520	0.0003*
vs. total OX40+PD-1− T cells	0.489	0.0004*	0.557	0.0001*

MDSCs, myeloid-derived suppressive cells; G-MDSCs, granulocytic MDSCs; M-MDSCs, monocytic MDSCs; Tregs, regulatory T cells.

*Statistically significant differences.