Table 1.
Summary of studies involved in LongITools
| Abbreviated study name and reference | Full study name | Study design | Geographic information | Year of establishment* | Sample size at baseline |
|---|---|---|---|---|---|
| Prospective birth cohorts | |||||
| ALSPAC G023 | Avon Longitudinal Study of Parents and Children Generation 0 | Prospective adult cohort | Home address geocoded to property and postcode level | 1991–1992 | 14,541 |
| ALSPAC G124 | Avon Longitudinal Study of Parents and Children Generation 1 | Prospective birth cohort | Home address geocoded to property and postcode level | 1991–1992 | 14,062 |
| ALSPAC G225 | Avon Longitudinal Study of Parents and Children Generation 2 | Prospective infant/child cohort | Home address geocoded to property and postcode level | 2012–2018 | 850 ongoing |
| DFBC26 | Dutch Famine Birth Cohort | Prospective birth cohort | Home address available at each visit | 1943 | 2,414 |
| EDEN27 | Etude des Déterminants pré et post natals précoces du développement psychomoteur et de la santé de l’Enfant (In French) | Prospective birth cohort | Home address geocoded to property and postcode level | 2003 | 2,002 |
| ELFE28 | Etude Longitudinale Française depuis l’Enfance (In French) | Prospective birth cohort | Home address available at each visit | 2011 | 18,329 |
| FinnGeDi29,30 | Finnish Gestational Diabetes Study | Prospective birth cohort | Home address available at baseline | 2009–2012 | 2,212 |
| Generation R31 | Generation R Study | Prospective birth cohort | Home address available at each visit | 2002–2006 | 9,778 |
| NFBC196626 | Northern Finland Birth Cohort 1966 | Prospective birth cohort | Home address available from 1966 | 1966 | 12,055 |
| NFBC198626 | Northern Finland Birth Cohort 1986 | Prospective birth cohort | Home address available from 1986 | 1986 | 9,432 |
| Prospective adult cohorts | |||||
| CONSTANCES32 | Cohorte des Consultants des Centres d’Examens de Santé (In French) | Prospective adult cohort | Home address available | 2012–2019 | 220,000 |
| RS I33 | Rotterdam Study, first cohort | Prospective adult cohort | Home address available | 1989 | 7,983 |
| RS II33 | Rotterdam Study, second cohort | Prospective adult cohort | Home address available | 2000 | 3,011 |
| RS III33 | Rotterdam Study, third cohort | Prospective adult cohort | Home address available | 2006 | 3,932 |
| OULU1935/45 | Born in Oulu in 1935 and 1945 | Prospective adult cohort | Home address available | 1935–1945 | 2,000 |
| Interventions and trials | |||||
| ELIPA34 | Elintarvikkeita Painonhallintaan (In Finnish) | RCT | Home address geocoded to property and postcode level | 2008 | 99 |
| Fibrefects35 | Grain Fibre Modification for Gut-Mediated Health Effects | RCT | Geocoding in process | 2011 | 25 |
| NOMA36 | Fat Quality on Blood Lipids and Immune Response | RCT | Home address available at baseline | 2012–2014 | 99 |
| PANIC37 | Physical Activity and Nutrition in Children Study | Controlled intervention | Home address available at baseline | 2007–2009 | 504 |
| SYSDIMET38 | Health Grain Intervention | RCT | Not available | 2007 | 102 |
| Administrative cohorts and Biobanks | |||||
| Borealis Biobank | Borealis Biobank of Northern Finland | Biobank | Home address available | 2015† | 500,000 |
| FMC | Finnish Maternity Cohort (managed by Borealis Biobank) | Biobank | Home address available upon request | 1983 | 950,000 |
| RCGP RSC | Royal College of General Practitioners Research & Surveillance Centre | Primary care sentinel network | Not available | 1990–2018 | 7,000,000 |
| UK Biobank | United Kingdom Biobank | Biobank | Not available | 2006 | 500,000 |
*Year of establishment in biobanks corresponds to the year from which samples are available.
†Diagnostic pathology tissue archives starting from 1978 to 8/2013 transferred to the biobank in addition to ongoing prospective biobank consent and sample collection.
RCT indicates randomized controlled trial.