Table 2.
List of identified and significantly changed metabolites in serum of dogs infected with B. canis versus healthy dogs obtained by targeted LC-MS metabolomics approach.
| Metabolites | Short Name | p-Value | Log2 (FC) | Classification |
|---|---|---|---|---|
| Serotonin | Serotonin | 1.14 × 10−6 | 2.59 | Biogenic amines |
| Methionine sulfoxide | Met-SO | 1.39 × 10−4 | 1.79 | Biogenic amines |
| Citrulline | Cit | 2.50 × 10−6 | 1.01 | Amino acids |
| Proline | Pro | 2.34 × 10−3 | 0.78 | Amino acids |
| Methionine | Met | 5.87 × 10−3 | 0.70 | Amino acids |
| Glycine | Gly | 1.45 × 10−2 | 0.42 | Amino acids |
| Aspartic acid | Asp | 4.02 × 10−3 | −0.83 | Amino acids |
| Phenylalanine | Phe | 2.32 × 10−6 | −1.06 | Amino acids |
| Putrescine | Putrescine | 2.09 × 10−4 | −1.22 | Biogenic amines |
| Kynurenine | Kynurenine | 7.76 × 10−8 | −1.59 | Biogenic amines |