Table 2.

Biomarkers associated with hepatocellular carcinoma were identified through single-cell sequencing.

Biomarker	Expression Pattern	Function	Ref.
MLXIPL	Molecular mechanism of glycolysis activated	Marker exhibits malignant biological behavior by activating glycolysis	[38]
LncRNA HOXA-AS2	High expression	Initiation and progression of HCC	[19]
CKS2, MIF, RPL12, HSP90AB1, and S100A6	High expression	Overall survival rate decreased	[39]
CCL14, CD5L, and APOC3	Low expression	Overall survival rate decreased	[39]
ZNF717	High-frequency mutation	Tumor suppressor activity regulating IL-6/STAT3 pathway	[40]
IGF2	Over expression	Growth regulation	[41]
Osteopontin	Over expression	Potentially regulate different immune cell types in TME; invasion and progression of HCC	[42]