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Evaluation of in vitro metabolic activity of human cells derived from colorectal carcinoma (CaCo-2) and human primary fibroblasts (MRC-5) treated with PLGA_OXA and PLGA_IO_OXA for 72 h determined by WST-1 assay. IC50—concentration of the nanoparticles required to achieve 50 % reduction in cell viability; SD—standard deviation (from four replicates).
| IC50 ± SD [µg·mL−1] of the Nanoparticles | ||
|---|---|---|
| Cell line | PLGA_OXA | PLGA_IO_OXA |
| CaCo-2 | 255 ± 11 | 560 ± 62 |
| MRC-5 | 525 ± 12 | 325 ± 31 |
