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. 2022 Jan 30;23(3):1626. doi: 10.3390/ijms23031626

Table 1.

Frequently reported dysregulated miRNAs in prostate cancer.

MiRNA Expression Sample Types, Author, Year
Tissue Serum/Plasma Urine
miR-21 Szczyrba, 2018; Wach, 2012 NA NA
Up Zedan, 2018;
Kumar, 2018
Porzycki, 2018; Kotb, 2014;
Egidi, 2013; Zedan, 2018;
Agaoglu, 2011; Mello Grand, 2018; Gao, 2016; Endzelinš, 2017—EVs
Ghorbanmehr, 2019;
Foj, 2017
miR-125b Down Zedan, 2018;
Schaefer, 2010
NA Fredsoe, 2018
Up Walter, 2013; Song, 2015 Mitchell, 2008; Zedan, 2018 NA
miR-141 Down NA Kachakova, 2014 Fredsoe, 2018
Up Szczyrba, 2010; Kumar, 2018; Nguyen, 2013;
Brase, 2014; Kelly, 2015
Mitchell, 2008; Porzycki, 2018; Cheng, 2013; Guo, 2018; Hao, 2016—EVs Bryant, 2012—EVs Ghorbanmehr, 2019;
Foj, 2017
miR-143 Down Szczyrba, 2010; Wach, 2012; Zedan, 2018; Kumar, 2018; Martens Uzunova, 2012 NA Stuopelyte, 2016
Rodriguez, 2017—EV
Up NA Nitchel, 2008; Zedan, 2018 NA
miR-145 Down Szczyrba, 2010; Wach, 2012; Porkka, 2007; Ozen, 2008; Kang, 2012; Zedan, 2018; Kurul, 2019; Schaefer, 2010; Larne, 2015, Kelly, 2015; Martens-Uzunova, 2012; Yfantis, 2008; Avgeris, 2013; Larne, 2013; Karatas, 2014 Wang, 2015, Zhu, 2015 Goto, 2017, Coarfa, 2016 Karadag, 2021, Liu, 2021 Leite, 2011 NA NA
Up NA Shen, 2012 Xu, 2017
miR-148 Down Feng, 2019, Walter, 2013 Arámbula-Meraz, 2020 NA Stuopelyte, 2016
Up Szczyrba, 2010; Martens-Uzunova, 2012;
Stuopelyte, 2016;
Lichner, 2015; Hart, 2013
Dybos, 2018; Al-Qatati, 2017;
Paunescu, 2019
NA
miR-182 Down NA NA NA
Up Wach, 2012; Schaefer, 2010; Yfantis, 2008;
Tsuchiyama, 2013;
Costa-Pinheiro, 2015;
Casanova-Salas, 2014
NA NA
miR185 Down Hellwinkel, 2013, Ostadrahimi, 2018 Mc Donald, 2019, Gurbuz, 2020 NA
Up Kristensen, 2016 NA NA
miR-200c Down Szczyrba, 2010; Wach, 2012; Yfantis, 2008 NA Fredsoe, 2018
Up NA Cheng, 2013
De Souza, 2017 Endzelinš, 2017—EVs
NA
miR-205 Down Scahefer, 2010;
Martens-Uzunova, 2012; Yfantis, 2008;
Tsuchiyama, 2013;
Verdoodt, 2013;
Kalogirou, 2013
Guo, 2018
Osipov, 2016
Fredsoe, 2018
Up Walter, 2013 NA NA
miR-221 Down Szczyrba, 2010; Wach, 2012; Zedan, 2018; Kurul, 2019; Schaefer, 2010; Yfantis, 2008; Porkka, 2007; Tsuchiyama, 2013; Casanova-Salas, 2014; Kneitzm, 2014 NA Fredsoe, 2018
Up Song, 2015 Kotb, 2014
Agaoglu, 2011
NA
miR-222 Down Wach, 2012; Schaefer, 2010; Martens-Uzunova, 2012; Porkka 2007;
Tsuchiyama, 2013
NA Fredsoe, 2018
Up NA NA NA
miR-375 Down Szczyrba, 2010; Wach, 2012; Schaefer, 2010;
Nguyen, 2013; Brase, 2011; Stuopelyte, 2016;
Yfantis, 2008;
Costa-Pinheiro, 2015; Haldrup, 2014; Nam, 2018
Kachakova, 2014 NA
Up NA Porzycki, 2018; Nguyen, 2013;
Brase, 2011; Cheng, 2013;
Haldrup, 2014; Wach, 2015;
Zedan, 2018; Gao, 2016;
Endzelinš, 2017; McDonald, 2018; Huang, 2015—EVs Bryant, 2012—EVs
Foj, 2017;
Stuopelyte, 2016
let-7a Down Szczyrba, 2010; Wach, 2012; Kelly, 2015; Porkka, 2007; Tian, 2015 Endzelinš, 2017—EV Fredsoe, 2018
Up Haldrup, 2014 Mello-Grand, 2018 NA

Note: Data were obtained from several research studies based on a meta-analysis by Song et al. [12] and Bertoli et al. [13]; EV: Extracellular vesicle.