Figure 10.

Fluorescence analysis of reactive oxygen species generation due to the POX activation using 0.5 µM of 2′,7′-dichlorofluorescin diacetate staining. Analysis performed on live cells using a survival chamber: 37 °C in 5% CO₂. MCF7 cells were incubated with the following drugs: 0.75 mM ibuprofen; 0.5 mM indomethacin; 0.375 mM diclofenac; 0.06 mM sulindac; 0.02 mM celecoxib; and 0.02 mM troglitazone, for the 4 h. Red fluorescence intensity represents amount of generated ROS.