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. 2022 Jan 28;23(3):1510. doi: 10.3390/ijms23031510
AMPK AMP-activated protein kinase
ATP adenosine triphosphate
COX cyclooxygenase
EGFR epidermal growth factor receptor
MAPK mitogen-activated protein kinase
mTOR mechanistic target of rapamycin
NSAIDs nonsteroidal anti-inflammatory drugs
P5C–∆1 pyrroline-5-carboxylate
P5CDH P5C dehydrogenase
PARP poly (ADP-ribose) polymerase
PGE2 prostaglandin E2
PPAR peroxisome proliferator-activated receptor
PRODH/POX proline dehydrogenase/proline oxidase
PYCR1 mitochondrial P5C reductase
PYCRL cytosolic P5C reductase
ROS reactive oxygen species