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. 2022 Jan 24;23(3):1294. doi: 10.3390/ijms23031294

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Overview of cimiRNA studies in MDD. (A) Fraction of human body fluids analyzed for cimiRNAs in MDD. (B) Clinical scales used for MDD diagnosis. (C) Age range of participants for MDD studies. (D) Number of MDD samples analyzed. (E) Extraction strategies employed for cimiRNA isolation. (F) Detection strategies used for cimiRNAs. (G) Types of studies illustrating either discovery phase or discovery accompanied by a validation phase. (H) Epidemiological data collected for depression study from various continents. (I) Percentage of males and females reported in depression studies.