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. 2022 Jan 27;23(3):1441. doi: 10.3390/ijms23031441

Table 1.

Current omics data available from DM1 studies.

Technique Type Sample Species Objective Reference Cite
CLIP-Seq Illumina Genome Analyzer II Embryonic fibroblasts Human, mouse Alternative polyadenylation GSE60487 [9]
2D WB and nano LC-MS/MS MALDI-TOF Voyager -DE-STR and Q-TOF MS Frontal cortex and hippocampus Mouse Proteome and phosphoproteome analysis Not provided [26]
Microarray ares_ucsc_mouse_59198_affyMouseA Skeletal muscle biopsies Mouse Alternative splicing GSE17986 [36]
RNA-Seq Illumina HiSeq 2000 Brain, heart, skeletal muscle, and cell cultures Mouse Transcriptome analysis GSE39911 [38]
CLIP-Seq Illumina Genome Analyzer II Brain, heart, skeletal muscle, and cell cultures Mouse RBP binding sites GSE39911 [38]
RNA-Seq Illumina HiSeq 2500 Quadriceps Mouse Transcriptome analysis PRJNA625451 [40]
RNA-Seq Illumina NextSeq 500 Embryonic stem cells, myoblast, myotubes Human Transcriptome analysis GSE160916 [41]
RNA-Seq Illumina HiSeq 2000 Skeletal muscle and heart biopsies and autopsies Human Transcriptome analysis GSE86356 [42]
Microarray Human Exon 1.0 ST array Skeletal muscle biopsies Human Alternative splicing GSE48828 [47]
LC-MS/MS EASY-nLC 1200-rbitrap Tribid MS Myoblasts Human Global proteome analysis PXD016056 [49]
iTraq Nano-LC-MS/MS Ultimate 3000 RSLC LTQ-Orbitrap Velos MS Cerebellum Mouse Global proteome analysis Not provided [51]
CLIP-Seq Illumina Genome Analyzer II Brain Human, mouse RBP binding sites, alternative polyadenylation GSE68890 [54]
Microarray Clariom D Arrays Cell culture Human Transcriptome analysis GSE164057 [55]
RNA-Seq Illumina HiSeq 2500 Astrocytes, oligodendrocytes, and neurons Mouse Transcriptome analysis GSE162093 [56]
2D WB and nano LC-MS/MS Nano RSLC-Q Astrocytes Mouse Phosphoproteome analysis PXD025011 [56]
RNA-Seq Illumina NextSeq 500 Frontal cortex biopsies Human Transcriptome analysis GSE157428 [57]
CLIP-Seq Illumina Genome Analyzer II Heart Chicken RBP binding sites GSE67360 [58]
RNA-Seq Illumina HiSeq 2000 Muscle, heart Mouse Transcriptome analysis GSE61893 [59]
CLIP-Seq Illumina Genome Analyzer II Muscle, heart Mouse RBP binding sites GSE61893 [59]
Microarray Illumina MouseWG-6 v2.0 expression beadchip Heart Mouse Transcriptome analysis GSE48991 [60]
RNA-Seq Illumina HiSeq 4000 Heart Mouse Transcriptome analysis GSE126771 [61]
RNA-Seq Illumina NovaSeq 6000 Heart Mouse Transcriptome analysis GSE164825 [62]
Microarray HumanHT-12 v3 Expression BeadChip Lens epithelial Human Transcriptome analysis E-MEXP-3365 [64]
RNA-Seq Illumina HiSeq 2500,
Illumina NextSeq 500
Thymus Human, mouse Transcriptome analysis GSE138691 [66]
RNA-Seq Illumina HiSeq 2500 Biceps brachii Human miRNA/mRNA interactions GSE108592 [73]
RNA-Seq Illumina NextSeq 500 Blood
Muscles, heart, and brain
Human,
mouse
miRNA analysis PRJEB46413 [74]
RNA-Seq Illumina NextSeq 550 Cell culture Human Transcriptome analysis GSE128844 [82]
RNA-Seq Illumina NextSeq 500 Quadriceps Mouse Transcriptome analysis PRJNA555349 [84]
RNA-Seq Illumina HiSeq 2000 Cell culture Human Transcriptome analysis GSE138789 [85]