Table 1.
Current omics data available from DM1 studies.
Technique | Type | Sample | Species | Objective | Reference | Cite |
---|---|---|---|---|---|---|
CLIP-Seq | Illumina Genome Analyzer II | Embryonic fibroblasts | Human, mouse | Alternative polyadenylation | GSE60487 | [9] |
2D WB and nano LC-MS/MS | MALDI-TOF Voyager -DE-STR and Q-TOF MS | Frontal cortex and hippocampus | Mouse | Proteome and phosphoproteome analysis | Not provided | [26] |
Microarray | ares_ucsc_mouse_59198_affyMouseA | Skeletal muscle biopsies | Mouse | Alternative splicing | GSE17986 | [36] |
RNA-Seq | Illumina HiSeq 2000 | Brain, heart, skeletal muscle, and cell cultures | Mouse | Transcriptome analysis | GSE39911 | [38] |
CLIP-Seq | Illumina Genome Analyzer II | Brain, heart, skeletal muscle, and cell cultures | Mouse | RBP binding sites | GSE39911 | [38] |
RNA-Seq | Illumina HiSeq 2500 | Quadriceps | Mouse | Transcriptome analysis | PRJNA625451 | [40] |
RNA-Seq | Illumina NextSeq 500 | Embryonic stem cells, myoblast, myotubes | Human | Transcriptome analysis | GSE160916 | [41] |
RNA-Seq | Illumina HiSeq 2000 | Skeletal muscle and heart biopsies and autopsies | Human | Transcriptome analysis | GSE86356 | [42] |
Microarray | Human Exon 1.0 ST array | Skeletal muscle biopsies | Human | Alternative splicing | GSE48828 | [47] |
LC-MS/MS | EASY-nLC 1200-rbitrap Tribid MS | Myoblasts | Human | Global proteome analysis | PXD016056 | [49] |
iTraq Nano-LC-MS/MS | Ultimate 3000 RSLC LTQ-Orbitrap Velos MS | Cerebellum | Mouse | Global proteome analysis | Not provided | [51] |
CLIP-Seq | Illumina Genome Analyzer II | Brain | Human, mouse | RBP binding sites, alternative polyadenylation | GSE68890 | [54] |
Microarray | Clariom D Arrays | Cell culture | Human | Transcriptome analysis | GSE164057 | [55] |
RNA-Seq | Illumina HiSeq 2500 | Astrocytes, oligodendrocytes, and neurons | Mouse | Transcriptome analysis | GSE162093 | [56] |
2D WB and nano LC-MS/MS | Nano RSLC-Q | Astrocytes | Mouse | Phosphoproteome analysis | PXD025011 | [56] |
RNA-Seq | Illumina NextSeq 500 | Frontal cortex biopsies | Human | Transcriptome analysis | GSE157428 | [57] |
CLIP-Seq | Illumina Genome Analyzer II | Heart | Chicken | RBP binding sites | GSE67360 | [58] |
RNA-Seq | Illumina HiSeq 2000 | Muscle, heart | Mouse | Transcriptome analysis | GSE61893 | [59] |
CLIP-Seq | Illumina Genome Analyzer II | Muscle, heart | Mouse | RBP binding sites | GSE61893 | [59] |
Microarray | Illumina MouseWG-6 v2.0 expression beadchip | Heart | Mouse | Transcriptome analysis | GSE48991 | [60] |
RNA-Seq | Illumina HiSeq 4000 | Heart | Mouse | Transcriptome analysis | GSE126771 | [61] |
RNA-Seq | Illumina NovaSeq 6000 | Heart | Mouse | Transcriptome analysis | GSE164825 | [62] |
Microarray | HumanHT-12 v3 Expression BeadChip | Lens epithelial | Human | Transcriptome analysis | E-MEXP-3365 | [64] |
RNA-Seq | Illumina HiSeq 2500, Illumina NextSeq 500 |
Thymus | Human, mouse | Transcriptome analysis | GSE138691 | [66] |
RNA-Seq | Illumina HiSeq 2500 | Biceps brachii | Human | miRNA/mRNA interactions | GSE108592 | [73] |
RNA-Seq | Illumina NextSeq 500 | Blood Muscles, heart, and brain |
Human, mouse |
miRNA analysis | PRJEB46413 | [74] |
RNA-Seq | Illumina NextSeq 550 | Cell culture | Human | Transcriptome analysis | GSE128844 | [82] |
RNA-Seq | Illumina NextSeq 500 | Quadriceps | Mouse | Transcriptome analysis | PRJNA555349 | [84] |
RNA-Seq | Illumina HiSeq 2000 | Cell culture | Human | Transcriptome analysis | GSE138789 | [85] |