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. Author manuscript; available in PMC: 2022 Feb 24.
Published in final edited form as: Chem Rev. 2021 Feb 5;121(4):2545–2647. doi: 10.1021/acs.chemrev.0c01122

Figure 16.

Figure 16.

Schematic diagram of 4-repeat (2N4R) and 3-repeat (2N3R) human tau isoforms. The microtubules binding region (MBD) is highlighted, and the sequences for the repeat units are shown along with the hexapeptides PHF6* and PHF6.