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. Author manuscript; available in PMC: 2022 Feb 24.
Published in final edited form as: Chem Rev. 2021 Feb 5;121(4):2545–2647. doi: 10.1021/acs.chemrev.0c01122

Figure 6.

Figure 6.

(A) Orthogonal view of Aβ40 structures (PDB entries 2LMN and 2LMP) spanning residues 9–40 and Aβ42 structures (PDB entries 2NAO and 5OQV) spanning residues 1–42. (B) Cryo-EM structure of Aβ42 showing the staggered arrangement of nonplanar Aβ42 subunits. (C) Cryo-EM structure of IAPP grown at physiological pH (PDB 6Y1A) spanning residues 13–37. The authors designed the figure with pymol.254