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. 2022 Jan 28;23(3):1499. doi: 10.3390/ijms23031499

Figure 3.

Figure 3

Role of DNA damage repair system in the longevity of lifespan. Successful DNA repair leads to the continuation of life activity/cell division, contrary to that failure in the DNA repair promotes programmed cell death (apoptosis). Direction of arrows indicate upregulation or downregulation of a process.