Figure 3.

Summary of the role of N2 neutrophils during tumor development. Tumor cells can recruit circulating neutrophils and induce a switch from N1 to N2 neutrophils. Indeed, N2 neutrophils play an important role in several stages of cancer development, like tumor initiation and growth or metastasis formation by secreting several key molecules. Figure created using Servier Medical Art available at http://smart.servier.com/ (accessed on 15 September 2021).