Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jan 23;23(3):1257. doi: 10.3390/ijms23031257

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Schematic representation of the 3 main hypotheses of NETs in cancer (1) DNA network formed by NETs may trap circulating cancer cells at the site of dissemination. (2) DNA network formed by NETs may increase local vascular permeability that facilitates the extravasation of cancer cells into the surrounding tissues. (3) The extracellular DNA represented by NETs can act as a chemotactic factor to attract cancer cells. Figure created using Servier Medical Art available at http://smart.servier.com/ (accessed on 15 September 2021).