Table 1.
Characteristics of CUR-loaded and empty polymeric nanocarriers.
System | Composition | CCUR [μM] | EE [%] | DH [nm] | PdI | ζ [mV] |
---|---|---|---|---|---|---|
1a | C12(TAPAMS)2/PLA/water | 77.9 | 92 | 195 ± 2 | 0.129 ± 0.01 | +42 ± 3 |
1b | C12(COONa)2/PLA/water | 80.9 | 95 | 334 ± 7 | 0.252 ± 0.02 | −81 ± 6 |
1c | Cremophor EL/PLA/water | 88.2 | 93 | 211 ± 4 | 0.149 ± 0.01 | −9 ± 1 |
2a | C12(TAPAMS)2/PLA/water | EMPTY | 186 ± 2 | 0.129 ± 0.01 | +41 ± 3 | |
2b | C12(COONa)2/PLA/water | EMPTY | 310 ± 6 | 0.232 ± 0.02 | −80 ± 6 | |
2c | Cremophor EL/PLA/water | EMPTY | 207 ± 3 | 0.147 ± 0.01 | −9 ± 1 |
DH: hydrodynamic diameter (Z-Ave), PdI: polydispersity index, ζ: zeta potential, EE: encapsulation efficiency.