Figure 1.
Decellularized MSC-derived ECM obtained after culturing the MSC for 2 days on standard tissue culture plates (ECM), on Matrigel-coated tissue culture plates (Matrigel-ECM), or on standard tissue culture plates with TGFβ1-supplemented medium (TGFβ1-induced ECM). Alcian blue staining was weak, suggesting low glycosaminoglycan content of the MSC-derived ECM, while picrosirius red staining was more distinct, demonstrating the presence of collagens. Note the fibrous structure of the TGFβ1-induced ECM.