Figure 3.

Relative gene expression of the extracellular matrix components collagen 1A2 (COL1A2), collagen 3A1 (COL3A1), tenascin-C (TNC), and decorin (DCN), the matrix metalloproteinases MMP1, MMP3, and MMP14, and their tissue inhibitors TIMP1 and TIMP2 in MSC after culture on the different MSC-derived ECM substrates (ECM, Matrigel-ECM, TGFβ1-ECM) or in the respective control conditions without MSC-derived ECM (tissue culture plastic (TCP), Matrigel). Gene expression differed significantly between groups designated with the same letter (p ≤ 0.007 in the post hoc tests). Data were obtained in n = 4 independent experiments.