Figure 4.

Modulating effects of OPAC on the transcriptional activities of AhR (A) and Nrf2 (B). HaCaT cells stably expressing the XRE- or ARE-reporter gene (XRE-NLuc::HaCaT or ARE-NLuc::HaCaT) were treated with OPAC for 6 h, and the reporter luciferase expression was measured as luminescence by a microplate luminometer. All values are expressed as means ± SD of three separate experiments. The different letters above the bars indicate significant differences among the treatments for each condition (p < 0.05).