Table 1.
Pregnancy Outcomes and clinical characteristics of natural cycle (NC-FET), artificial hormone support cycle without downregulation (AC-FET) and artificial hormone support cycle with agonist downregulation (ACDR-FET) groups.
| NC-FET (1) | AC-FET (2) | ACDR-FET (3) | p-Value | |
|---|---|---|---|---|
| Maximum Endometrial Thickness (mm) a |
9.5 ± 1.95 | 9.4 ± 1.7 | 9.9 ± 1.9 | <0.001 d |
| Live Birth b | 175/430 (40.7%) | 978/2658 (36.8%) | 716/1949 (36.7%) | 0.27 c |
| Clinical Pregnancy b | 206/430 (47.9%) | 1121/2658 (42.2%) | 865/1949 (44.4%) | 0.052 c |
| Implantation a | 0.46 ± 0.5 | 0.44 ± 0.49 | 0.46 ± 0.49 | 0.56 d |
| Biochemical Pregnancy b | 246/430 (57.2%) | 1476/2658 (55.5%) | 1136/1949 (58.3%) | 0.17 c |
| Miscarriage b | 36/243 (14.8%) | 252/1476 (17%) | 223/1136 (19.6%) | 0.1 c |
| Multiple Pregnancy b | 15/206 (7.3%) | 55/1121 (4.9%) | 53/865 (6.1%) | 0.28 c |
| Ectopic Pregnancy b | 1/246 (0.4%) | 6/1476 (0.4%) | 4/1136 (0.35%) | 0.97 c |
a: values are mean ± standard deviation; b: values are percentages; c: Chi-square test was used for dichotomous variables; d: Kruskal–Wallis test was used for continuous variables. Mann–Whitney test was also used for continuous variables. Maximum Endometrial Thickness p-value 1–2 > 0.05; p-value 1–3 < 0.05; p-value 2–3 < 0.05. Implantation p-value 1–2 > 0.05; p-value 1–3 > 0.05; p-value 2–3 > 0.05. p-value < 0.05 is considered statistically significant.