Table 3.
VISUHEALTH-AI DR gradability and hospital-referable performance evaluation by site, age category, and visual acuity.
| Gradability | Hospital-Referable | ||||
|---|---|---|---|---|---|
| Sensitivity (95% CI) | Specificity (95% CI) | Sensitivity (95% CI) | Specificity (95% CI) | ||
| Site | 1 | 73.93 (71.57–76.19) | 98.66 (95.24–99.84) | 98.26 (94.99–99.64) | 71.01 (68.56–73.37) |
| 2 | 89.45 (87.85–90.9) | 92.31 (87.81–95.54) | 83.23 (78.64–87.18) | 86.05 (84.21–87.76) | |
| 3 | 70.77 (65.81–75.38) | 82.86 (77.07–87.7) | 85.14 (79.76–89.54) | 68.08 (62.95–72.91) | |
| 4 | 97.61 (96.4–98.5) | 72.41 (63.34–80.3) | 78.46 (70.4–85.19) | 94.81 (93.16–96.16) | |
| 5 | 83.76 (77.85–88.62) | 85.29 (68.94–95.05) | 84.21 (68.75–93.98) | 79.27 (72.87–84.76) | |
| 6 | 88.6 (86.38–90.57) | 94.68 (88.02–98.25) | 86.81 (80.16–91.87) | 82.16 (79.47–84.63) | |
| 7 | 97.97 (96.85–98.77) | 68.35 (59.92–75.97) | 73.48 (67.28–79.06) | 94.08 (92.27–95.58) | |
| 8 | 82.94 (81.0–84.75) | 91.51 (86.91–94.89) | 90.5 (86.86–93.41) | 76.68 (74.43–78.82) | |
| 9 | 96.78 (95.57–97.73) | 56.29 (50.64–61.82) | 69.41 (64.21–74.27) | 89.05 (87.05–90.84) | |
| 10 | 95.55 (94.21–96.65) | 46.3 (42.7–49.93) | 54.53 (51.02–58.01) | 89.66 (87.74–91.36) | |
| 11 | 94.26 (90.96–96.62) | 81.94 (71.11–90.02) | 91.4 (83.75–96.21) | 87.64 (83.15–91.28) | |
| 12 | 99.31 (98.64–99.7) | 41.85 (35.9–47.98) | 60.64 (54.67–66.38) | 92.93 (91.28–94.34) | |
| 13 | 97.05 (95.26–98.31) | 47.92 (33.29–62.81) | 58.82 (46.23–70.63) | 89.10 (86.11–91.64) | |
| 14 | 94.4 (92.18–96.14) | 78.57 (49.2–95.34) | 88.89 (73.94–96.89) | 87.07 (83.97–89.76) | |
| 15 | 96.45 (94.11–98.04) | 43.02 (32.39–54.15) | 50.00 (39.62–60.38) | 91.93 (88.74–94.45) | |
| 16 | 94.43 (92.22–96.16) | 84.62 (54.55–98.08) | 86.67 (69.28–96.24) | 85.1 (81.87–87.95) | |
| 17 | 99.69 (98.89–99.96) | 38.96 (28.05–50.75) | 62.83 (53.24–71.74) | 90.85 (88.28–93.01) | |
| 18 | 94.02 (92.0–95.65) | 62.28 (56.91–67.44) | 69.36 (64.31–74.09) | 88.18 (85.52–90.5) | |
| 19 | 97.92 (96.59–98.83) | 90.91 (58.72–99.77) | 94.74 (82.25–99.36) | 88.31 (85.68–90.61) | |
| 20 | 89.12 (87.3–90.76) | 84.21 (76.2–90.37) | 66.02 (59.11–72.46) | 85.38 (83.26–87.33) | |
| Age | ≤40 | 91.61 (88.57–94.05) | 66.67 (34.89–90.08) | 63.64 (40.66–82.8) | 91.41 (88.3–93.91) |
| 41–60 | 93.13 (92.64–93.59) | 61.36 (58.51–64.15) | 69.57 (67.28–71.79) | 89.21 (88.6–89.79) | |
| 61–70 | 88.14 (87.11–89.12) | 65.41 (62.57–68.17) | 72.72 (70.28–75.06) | 80.09 (78.79–81.35) | |
| >70 | 86.35 (84.64–87.93) | 69.30 (66.26–72.23) | 75.44 (72.68–78.06) | 74.61 (72.45–76.68) | |
| Visual Acuity | Normal | 91.41 (90.93–91.87) | 62.15 (60.06–64.21) | 69.39 (67.61–71.12) | 86.73 (86.14–87.3) |
| VI | 90.71 (89.59–91.74) | 67.95 (64.81–70.98) | 75.27 (72.62–77.79) | 81.56 (80.04–83.01) | |
| Severe VI | 82.46 (74.21–88.94) | 80.82 (69.92–89.1) | 87.06 (78.02–93.36) | 71.57 (61.78–80.06) | |
| Blind | 78.79 (70.82–85.42) | 81.43 (73.98–87.5) | 86.84 (80.41–91.77) | 65.00 (55.76–73.48) | |
| All data | 91.22 (90.79–91.64) | 65.06 (63.40–66.69) | 72.08 (70.68–73.46) | 85.65 (85.11–86.18) | |