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. 2022 Jan 20;11(3):527. doi: 10.3390/jcm11030527

Table 4.

Frequency of meibomian gland features in the middle-third of the lids.

Features All Male Female p-Value
UL LL p * UL LL p * UL LL p * UL 1 LL 1
Median (Q1, Q3) Median (Q1, Q3) Median (Q1, Q3) Median (Q1, Q3) Median (Q1, Q3) Median (Q1, Q3)
Total number 8.0 (7.5, 8.5) 6.5 (6, 7.0) <0.001 8.0 (7.3, 8.5) 6.5 (6.0, 7.0) 8.0 (7.5, 8.5) 6.5 (6.0, 7.0) 0.292 0.305
Distorted 3.0 (2.0, 3.5) 2.0 (1.5, 3.0) <0.001 3.0 (2.0, 3.5) 2.0 (1.5, 2.6) 2.8 (2.0, 3.4) 2.5 (1.5, 3.0) 0.327 0.474
Tortuous 3.0 (2.5, 4.0) 0 (0, 0.5) <0.001 3.0 (2.5, 3.8) 0 (0, 0.5) 3.0 (2.5, 4.0) 0 (0, 1.0) 0.797 0.739
Hooked 1.0 (0.5, 2.0) 0 (0, 0) <0.001 1.0 (0.5, 2.0) 0 (0, 0) 1.0 (0.5, 2.0) 0 (0, 0.5) 0.762 0.014
Short 3.0 (2.5, 4.5) 2.0 (2.0, 3.0) <0.001 3.0 (2.5, 4.5) 2.0 (1.9, 3.0) 3.0 (2.5, 4.5) 2.0 (2.0, 3.0) 0.596 0.826
Overlap 3.0 (2.0, 4.5) 0 (0, 1.5) <0.001 3.0 (2.0, 4.5) 0 (0, 1.1) 2.5 (1.1, 4.4) 0 (0, 1.8) 0.164 0.961
Ghost 0 (0, 2.5) 0 (0, 0) <0.001 0 (0, 2.5) 0 (0, 0) 0 (0, 1.4) 0 (0, 0) 0.367 0.801
Drop-out 0 (0, 0) 0 (0, 0.5) 0.019 0 (0, 0) 0 (0, 0.5) 0 (0, 0) 0 (0.0, 0.5) 0.532 0.687
Other Features n (%) n (%) p # n (%) n (%) p # n (%) n (%) p # p-Value
UL 2
p-Value
LL 2
Tadpoling (yes) 20 (18.9%) 7 (6.1%) 0.0473 10 (18.5%) 4 (6.9%) 1.000 10 (19.2%) 3 (5.3%) 1.000 1.000 1.000
Gaps (yes) 101 (96.2) 91 (64.1%) 0.015 52 (98.1%) 38 (65.5%) 0.377 49 (94.2%) 39 (68.4%) 0.037 0.363 0.843
No lid margin extent (yes) 5 (4.8%) 36 (31.3%) 0.002 2 (3.8%) 18 (31.0%) 0.076 3 (5.8%) 18 (31.6%) 0.031 0.678 1.000
Fluffy areas (yes) 71 (67.6%) 114 (99.1%) 0.324 33 (62.3%) 57 (98.3%) 0.377 38 (73.1%) 57 (100%) NA 0.298 1.000

UL = upper lid; LL = lower lid. 1. Differences between males and females evaluated with Student t-test with normally distributed data and with Mann–Whitney test with non-normally distributed data. 2. Differences between males and females evaluated with Chi-square test. * Differences between upper and lower lids evaluated with Wilcoxon signed rank test. # Differences between upper and lower lids evaluated with Chi-square test.