Table 1.
Clinical characteristics and mortality of patients with acute heart failure with/without history of cancer.
| Variable | Acute HF with Cancer (n = 394) |
Acute HF without Cancer (n = 2733) |
p |
|---|---|---|---|
| Age | 79.29 +/− 10.2 | 78.83 +/− 11.05 | p = 0.439 |
| Sex (male) | 247 (63%) | 1295 (47%) | p < 0.001 |
| NYHA III-IV | 82/383 (21%) | 639/2683 (24%) | p = 0.334 |
| LVEF | 53.28% +/− 15.78 | 50.63% +/− 16.14 | p = 0.018 |
| NTpro-BNP | 8933 pg/mL +/− 1247 | 8334 pg/mL +/− 349 | p = 0.561 |
| Charlson score | 4.42 +/− 1.7 | 3.44 +/− 1.86 | p < 0.001 |
| Comorbid conditions | |||
| Hypertension | 332/393 (85%) | 2322/2726 (85%) | p = 0.705 |
| Diabetes | 168/392 (43%) | 1257/2724 (46%) | p = 0.23 |
| Ischemic cardiopathy | 113/390 (29%) | 885/2698 (33%) | p = 0.13 |
| Atrial fibrillation | 219/393 (56%) | 1556/2723 (57%) | p = 0.624 |
| Valvulopathy | 176/377 (47%) | 1141/2621 (44%) | p = 0.267 |
| COPD | 104/386 (27%) | 704/2699 (26%) | p = 0.711 |
| Chronic renal failure | 210/393 (53%) | 1254/2708 (46%) | p = 0.009 |
| Previous cerebrovascular disease | 75/392 (19%) | 592/2700 (22%) | p = 0.237 |
| Anaemia | 211/394 (54%) | 1302/2713 (48%) | p = 0.040 |
| In-hospital and 6-month follow-up mortality | 110/3573 (31%) | 637/2466 (26%) | p = 0.046 |
Legend: NYHA: New York Heart Association functional class; LVEF: left ventricular ejection fraction; COPD: chronic obstructive pulmonary disease.