Table 1.
Summary of animal mass and isometric torque values over time
| Tourniquet Only | Low Dose | High Dose | |
|---|---|---|---|
| Sample size | 12 | 6 | 6 |
| Baseline | |||
| Body mass, g | 332.7 ± 13.5 | 328.0 ± 5.0 | 344.4 ± 8.2 |
| Maximal isometric torque, Nmm/kg | 104.6 ± 1.1 | 104.7 ± 2.1 | 104.6 ± 1.4 |
| Tourniquet application | |||
| Body mass, g | 344.3 ± 13.2 | 371.5 ± 6.4 | 369.1 ± 6.6 |
| 1 wk postinjury | |||
| Body mass, g | 333.1 ± 11.0 | 351.8 ± 5.2 | 351.7 ± 5.2 |
| Maximal isometric torque, Nmm/kg | 12.2 ± 4.0 | 43.9 ± 9.7* | 19.8 ± 10.7 |
| Ratio of maximal isometric torque to baseline, Nmm/kg:Nmm/kg | 0.11 ± 0.04 | 0.42 ± 0.09* | 0.19 ± 0.11 |
| 2 wk postinjury | |||
| Body mass, g | 348.7 ± 9.2 | 367.5 ± 6.0 | 366.2 ± 4.7 |
| Maximal isometric torque, Nmm/kg | 20.4 ± 6.9 | 68.2 ± 10.6*† | 31.4 ± 13.0 |
| Ratio of maximal isometric torque to baseline, Nmm/kg:Nmm/kg | 0.20 ± 0.07 | 0.65 ± 0.10*† | 0.31 ± 0.13 |
| 4 wk postinjury | |||
| Body mass, g | 390.3 ± 9.1 | 395.1 ± 6.0 | 388.5 ± 5.2 |
| Maximal isometric torque, Nmm/kg | 50.2 ± 7.8 | 89.7 ± 9.3*† | 57.5 ± 15.5 |
| Ratio of maximal isometric torque to baseline, Nmm/kg:Nmm/kg | 0.48 ± 0.07 | 0.85 ± 0.08*† | 0.56 ± 0.15 |
Data presented as means ± SE. *Significantly different (P < 0.05) compared with Tourniquet-Only group for the time point, †significantly different (P < 0.05) compared to High-Dose group for the time point; body mass and postinjury torque data analyzed using Fisher’s least significant difference (LSD) pairwise comparisons following 2-way repeated-measures ANOVA for matched samples, baseline torque data analyzed with ordinary 1-way ANOVA.