Table 2.

Blood composition and flows: baseline and hyperkalemia

	Baseline (A1)	Hyperkalemia (B3)
Plasma flow, µL/min
Cortical labyrinth	2,700.0	2,700.0
Medullary ray	311.0	311.0
SAVR	192.0	192.0
LAVR	37.2	37.2
Hematocrit, %	45	45
Po2, mmHg
Cortical labyrinth	65	65
Medullary ray	65	65
Outer medulla	35	35
Inner medulla	35 → 7	35 → 7
Interstitial pressure, mmHg
Cortical labyrinth	10.0	10.0
Medullary ray	10.0	10.0
GFR, µL/min
Superficial	741.0	652.8
Juxtamedullary	767.4	699.0
Filtration fraction	32%	29%
Plasma concentration
Na+, mM	144.00	144.00
K+, mM	5.00	6.50
Cl−, mM	118.40	119.90
${\text{HCO}}_3^{-}$, mM	25.0	25.0
H2CO3, µM	3.53	3.53
CO2, mM	1.20	1.20
${\text{HPO}}_4^{2-}$, mM	2.10	2.10
${\text{H}}_{\text{2}}{\text{PO}}_{\text{4}}^{-}$, mM	0.50	0.50
Urea, mM	5.00	5.00
NH3, µM	1.83	1.83
${\text{NH}}_4^{+}$, mM	0.10	0.10
HCO2−, mM	1.00	1.00
H2CO2, µM	0.22	0.22
Glucose, mM	5.00	5.00
Protein, g/dL	8.00	8.00
Ammoniagenesis, nmol/s/cm2
SFPCT	0.150	0.075
SFPST	0.015	0.0075
JMPCT	0.300	0.150
JMPST	0.030	0.015

In column 2, the bold font shows the change in arterial composition used to represent hyperkalemia and also the change in the reference rate for ammoniagenesis. GFR, glomerular filtration rate; JMPCT and JMPST, juxtamedullary proximal convoluted tubule and proximal straight tubule; LAVR, long ascending vasa recta; SAVR, short ascending vasa recta; SFPCT and SFPST, superficial proximal convoluted tubule and proximal straight tubule, respectively.