. 2022 Jan 10;322(2):F225–F244. doi: 10.1152/ajprenal.00413.2021

Table 9.

Whole kidney flows and fluxes in hyperkalemia with regulated transport and no tubuloglomerular feedback

Case C1	PCT	LOH	DCT	CNT	CD	Urine
Delivery
Na⁺, µmol/min	217.2	86.0	28.2	20.7	13.1	9.0
K⁺	9.80	3.75	1.05	1.45	4.29	3.20
${NH}_{4}^{+}$	0.15	0.63	0.34	1.04	1.30	0.94
F_v, µL/min	1,508	600	281	263	175	66
Relative to filtered load
Na⁺	100.0%	39.6%	13.0%	9.5%	6.1%	4.1%
K⁺	100.0%	38.3%	10.7%	14.8%	43.7%	32.6%
${NH}_{4}^{+}$	100.0%	426.9%	228.9%	698.9%	880.7%	634.2%
F _v	100.0%	39.8%	18.6%	17.5%	11.6%	4.4%
Reabsorption						Total
Na⁺, µmol/min	131.2	57.9	7.5	7.6	4.1	208.2
K⁺	6.05	2.71	−0.40	−2.83	1.09	6.61
${NH}_{4}^{+}$	−0.48	0.29	−0.70	−0.27	0.37	−0.79
J_v, µL/min	909	319	17	88	109	1442
Relative to filtered load
Na	60.4%	26.6%	3.4%	3.5%	1.9%	95.9%
K	61.7%	27.6%	−4.1%	−28.9%	11.1%	67.4%
NH₄	−326.9%	198.1%	−470.0%	−181.8%	246.5%	−534.2%
J _v	60.2%	21.2%	1.2%	5.8%	7.2%	95.6%

Case C2	PCT	LOH	DCT	CNT	CD	Urine
Delivery
Na⁺, µmol/min	217.2	86.6	29.6	24.5	16.6	12.0
K⁺	9.80	3.78	0.96	1.41	4.24	3.39
${NH}_{4}^{+}$	0.15	0.59	0.26	1.02	1.28	1.00
F_v, µL/min	1,508	603	288	273	198	82
Relative to filtered load
Na⁺	100.0%	39.9%	13.6%	11.3%	7.6%	5.5%
K⁺	100.0%	38.5%	9.8%	14.4%	43.2%	34.6%
${NH}_{4}^{+}$	100.0%	397.5%	173.2%	688.9%	865.7%	676.5%
F _v	100.0%	40.0%	19.1%	18.1%	13.1%	5.5%
Reabsorption						Total
Na⁺, µmol/min	130.6	57.0	5.1	7.9	4.6	205.3
K⁺	6.03	2.82	−0.46	−2.82	0.84	6.41
${NH}_{4}^{+}$	−0.44	0.33	−0.76	−0.26	0.28	−0.85
J_v, µL/min	905	315	15	75	116	1426
Relative to filtered load
Na	60.1%	26.2%	2.3%	3.7%	2.1%	94.5%
K	61.5%	28.8%	−4.7%	−28.8%	8.6%	65.4%
NH₄	−297.5%	224.4%	−515.7%	−176.8%	189.2%	−576.5%
J _v	60.0%	20.9%	1.0%	5.0%	7.7%	94.6%

Case C3	PCT	LOH	DCT	CNT	CD	Urine
Delivery
Na⁺, µmol/min	217.2	83.8	28.1	23.3	14.9	9.8
K⁺	9.80	3.58	0.72	1.21	4.42	3.64
${NH}_{4}^{+}$	0.15	0.31	0.11	0.55	0.70	0.55
F_v, µL/min	1,508	583	276	260	182	71
Relative to filtered load
Na⁺	100.0%	38.6%	13.0%	10.7%	6.8%	4.5%
K⁺	100.0%	36.5%	7.4%	12.3%	45.0%	37.1%
${NH}_{4}^{+}$	100.0%	208.1%	77.6%	372.0%	475.7%	373.3%
F _v	100.0%	38.7%	18.3%	17.2%	12.1%	4.7%
Reabsorption						Total
Na, µmol/min	133.4	55.7	4.8	8.5	5.1	207.4
K	6.22	2.86	−0.49	−3.21	0.78	6.17
NH₄	−0.16	0.19	−0.44	−0.15	0.15	−0.40
J_v, µL/min	925	307	16	78	111	1,437
Relative to filtered load
Na⁺, µmol/min	61.4%	25.7%	2.2%	3.9%	2.4%	95.5%
K⁺	63.5%	29.2%	−5.0%	−32.7%	8.0%	62.9%
${NH}_{4}^{+}$	−108.1%	130.5%	−294.5%	−103.7%	102.4%	−273.3%
J_v, µL/min	61.3%	20.4%	1.1%	5.2%	7.4%	95.3%

CD, collecting duct from the cortical collecting duct through the inner medullary collecting duct; CNT, connecting tubule; DCT, distal convoluted tubule; F_v, axial volume flow; J_v, volume reabsorption; LOH, loop of Henle (all tubules from the proximal straight tubule through the cortical ascending Henle’s loop); PCT, all proximal convoluted tubules.