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. 2022 Jan 29;11(3):721. doi: 10.3390/jcm11030721

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Heatmap of top 30 features derived from ANOVA for individual patients (left) and group mean averages (right) presented without clustering. AC, acylcarnitine; DMA, dimethylarginine; lysoPC, monoacyl-glycerophosphocholine; PC aa, diacyl-glycerophosphocholine; PC ae, alkyl-acyl-glycerophosphocholine; PUFA, poly-unsaturated fatty acid; SM, sphingomyelin; abundance of each of the metabolites is presented by colour ranging from low (blue) over average (white) to high (red); adapted from MetaboAnalyst 4.0.