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. 2022 Feb 5;23(3):1826. doi: 10.3390/ijms23031826

Figure 1.

Figure 1

Insulin release (Plasma IRI: immunoreactive insulin) in response to the intravenous administration of glucose in normal and diabetic subjects. Mean fasting plasma glucose concentrations: normal subjects = 85 ± 3 mg/dL; noninsulin-dependent diabetic subjects (NIDDs) = 180 ± 10 mg/dL; and insulin-dependent diabetic subjects (IDDs) = 325 ± 33 mg/dL. Note the lack of first-phase insulin response and the preservation of second-phase insulin response in noninsulin-dependent diabetic subjects, and the total lack of any response to glucose in the insulin-dependent diabetic subjects. Pfeifer MA et al. AM J Med 70:579, 1981.