Figure 11.

Resting ACM and ACM-sAβO42 had opposite effects on endothelial properties and protein expression of junctional proteins. (A) TEER value of the bEnd.3 monolayer after the treatment of ACM sAβO42 (10 µM for 24 h), resting ACM (24 h), or exogenous sAβO42 alone or in combination. (B) The protein expression levels of tight junction proteins ZO-1 and claudin-5. Data are shown as means ± SD of at least three independent experiments and were analyzed by one-way ANOVA followed by a post hoc Dunnett’s test and a post hoc Tukey’s test. * p ≤ 0.1, ** p ≤ 0.01, *** p ≤ 0.001, **** p ≤ 0.0001 vs. control group or between two compared groups.