Table 1.
Granzyme chromosomal location and size in mice (A) and humans (B) 1.
| (A) | |||
|---|---|---|---|
| Chromosome | Location | Length within Genome (bp) | |
| Gzm K | 13 c | chr13:113,308,172-113,317,431 | 9260 |
| Gzm A | 13 c | chr13:113,230,361-113,237,515 | 7155 |
| Gzm B | 14 c | chr14:56,496,295-56,499,717 | 3423 |
| Gzm C | 14 c | chr14:56,468,898-56,472,113 | 3216 |
| Gzm F | 14 c | chr14:56,442,720-56,448,874 | 6155 |
| Gzm N | 14 c | chr14:56,403,254-56,412,056 | 8803 |
| Gzm G | 14 c | chr14:56,394,039-56,397,036 | 2998 |
| Gzm D | 14 c | chr14:56,367,013-56,370,065 | 3053 |
| Gzm E | 14 c | chr14:56,355,083-56,358,082 | 3000 |
| Gzm M | 10 c | chr10:79,524,854-79,531,095 | 6242 |
| (B) | |||
| Chromosome | Location | Length within Genome (bp) | |
| Gzm K | 5 | chr5:55,024,256-55,034,570 | 10,315 |
| Gzm A | 5 | chr5:55,102,646-55,110,252 | 7607 |
| Gzm B | 14 c | chr14:24,630,954-24,634,190 | 3237 |
| Gzm H | 14 c | chr14:24,606,480-24,609,685 | 3206 |
| Gzm M | 19 c | chr19:544,053-549,922 | 5870 |
1 Gzms are clustered on 3 different chromosomes, the Gzm A locus (blue), the Gzm B locus (orange), and the Gzm M locus (gray). Genome data was extracted from the UCSC genome browser using the Mouse Jun 2020 GRCm39/mm39 assembly and the Human Dec 2013 GRCh38/hg38 assembly. Gzms located on the complementary strand of the chromosome are identified with a “c” in the chromosome column.