Table 1.
Baseline characteristics of patients stratified by absolute lymphocyte count.
| Variables | Total Patients | Absolute Lymphocyte Count | p Value | |
|---|---|---|---|---|
| <1.1 × 109/L | ≥1.1 × 109/L | |||
| Patients, n (%) | 4485 | 2409 (53.7) | 2076 (46.3) | |
| Age, years | 60 (46–72) | 64 (52–75) | 57 (41–70) | <0.001 |
| Male, n (%) | 2311 (51.5) | 1413 (58.7) | 898 (43.3) | <0.001 |
| Race, n (%) | <0.001 | |||
| White | 756 (16.9) | 451 (18.7) | 305 (14.8) | |
| Black | 1358 (30.3) | 593 (24.6) | 765 (36.8) | |
| Hispanic | 2146 (47.8) | 1244 (51.6) | 902 (43.4) | |
| Asian | 49 (1.1) | 31 (1.3) | 18 (0.9) | |
| Other | 176 (3.9) | 90 (3.7) | 86 (4.1) | |
| Comorbidity, n (%) | ||||
| Diabetes | 1813 (40.4) | 1000 (41.5) | 813 (39.2) | 0.109 |
| Hypertension | 2953 (65.8) | 1701 (70.6) | 1252 (60.3) | <0.001 |
| COPD | 374 (8.3) | 234 (9.7) | 140 (6.7) | <0.001 |
| Chronic kidney disease | 670 (14.9) | 399 (16.6) | 271 (13.1) | <0.001 |
| Coronary heart disease | 705 (15.7) | 420 (17.4) | 285 (13.7) | <0.001 |
| Malignancy | 231 (5.2) | 136 (5.7) | 95 (4.6) | 0.106 |
| Obesity | 1061 (23.7) | 835 (34.7) | 226 (10.9) | <0.001 |
| Smoking | 1089 (24.3) | 623 (25.9) | 466 (22.4) | 0.008 |
| Laboratory testing | ||||
| CRP, mg/L | 6.6 (2.8–12.1) | 7.4 (3.4–12.9) | 5.6 (2.2–10.9) | <0.001 |
| D-dimer, mg/L | 0.9 (0.5–1.8) | 0.9 (0.5–1.9) | 0.9 (0.5–1.8) | 0.142 |
| IL-6, mg/L | 36.2 (13.4–85.9) | 39.8 (14.7–94.2) | 30.6 (12.2–73.8) | 0.019 |
| LDH, U/L | 317 (243–432) | 337 (258–450) | 293 (226–398) | <0.001 |
| Creatinine, mg/L | 0.9 (0.7–1.2) | 0.9 (0.7–1.2) | 0.8 (0.6–1.1) | <0.001 |
Data given as median and interquartile range (IQR) or n (%); COPD, chronic obstructive pulmonary disease; CRP, C-reactive protein; IL-6, interleukin-6; LDH, lactate dehydrogenase.