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Mean (±S.E.M.) of cumulative changes in physical activity, measured as the mean distance traveled in meters during the 6 h following injections of saline (panel A; n = 8), nicotine (panel B; n = 10), nornicotine (panel C; n = 10), anabasine (panel D; n = 10), or anatabine (panel E; n = 10) for the final day of baseline (day 0), and days 1 and 6 of treatment injections. * p < 0.05, ** p < 0.01 difference from baseline activity (day 0) at the indicated hour.
