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. 2021 Dec 17;21(1):86–100. doi: 10.1080/15384101.2021.2009986

Figure 5.

Figure 5.

MiR-146b-5p bound to YAP 3ʹUTR, and circ_0014235 regulated YAP expression by targeting miR-146b-5p. (a) The sequence fragments of YAP 3ʹUTR wt and YAP 3ʹUTR mut were shown. (b) The relationship between miR-146b-5p and YAP was verified by dual-luciferase reporter assay. (c) The expression of YAP and p-YAP in PC9/GR and HCC827/GR, and their parental cells was detected by Western blot. (d) The expression of YAP and p-YAP in PC9/GR and HCC827/GR cells transfected with sh-circ_0014235 or sh-circ_0014235+ anti-miR-146b-5p was measured by Western blot. *P < 0.05.