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. 2022 Jan 3;21(2):202–218. doi: 10.1080/15384101.2021.2015669

Figure 2.

Figure 2.

CRO regulated the abnormal CD68, LXR-α, and PPARγ levels in the aorta of mice with AS.

The levels of CD68, LXR-α, and PPARγ in the aorta of mice after being fed with HFD and CRO treatment or not were determined by immunohistochemistry (magnification × 40). ***P < 0.001, vs. Sham; ##P < 0.01, ###P < 0.001, vs. HFD. AS: Atherosclerosis, CRO-L: low dose of Crocin, CRO-H: high dose of Crocin, HFD: high-fat diet; CD68: cluster of difference 68; LXR-α: Liver X Receptor-α; PPARγ: Peroxisome Proliferator-Activated Receptor γ.