Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jan 3;21(2):202–218. doi: 10.1080/15384101.2021.2015669

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

PMC Copyright notice

Figure 4. — CRO inhibited the lipid droplets formation and regulated the levels of lipid metabolism-related factors in LPA-induced macrophages

(A) The viability of RAW264.7 macrophages after being treated with different concentrations of CRO was detected by MTT assay. (B) The formation of lipid droplets in RAW264.7 macrophages after being treated with LPA or CRO was detected by Oil-red-O staining (magnification × 200). (C) The levels of CE/TC in RAW264.7 macrophages after being treated with LPA or CRO were detected and calculated. (D-I) The protein/β-actin expressions of PPARγ/LXR-α, PCSK9, CD36, and ABCA1 of RAW264.7 macrophages after treated with LPA or CRO were detected by Western blot. β-actin was used as an internal control. ***P < 0.001, vs. Control; ^#P < 0.05, ^##P < 0.01, ^###P < 0.001, vs. LPA; ^P< 0.05, ^^P< 0.01, ^^^P< 0.001, vs. LPA + CRO-20. CRO: Crocin, LPA: lysophosphatidic acid, CE: cholesteryl ester, TC: total cholesterol.