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. 2022 Feb 10;13(1):191–214. doi: 10.1080/21505594.2022.2026037

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — C. auris interacts with immune cells and is efficiently killed during ex vivo whole blood infection. (a) Survival of C. auris, C. albicans, and C. glabrata in human whole blood was determined 30, 60, 120, and 240 minutes post infection (mpi) by CFU quantification relative to time point 0 mpi as 100%. n = 6, mean ± SD (b) Exemplary microscopic pictures of blood smears prepared at indicated time points from C. auris infected whole blood. Arrows indicate fungal and human immune cells. 100 x magnification (c) Association of fungal cells with immune cells was determined by fluorescence activated cell sorting (FACS) analyses at 60 mpi and 240 mpi. n = 3, mean ± SD for independent experiments using different donors.