Tab. 2 Aktuelle selektive Östrogenrezeptor-Degradierer (SERD).
| SERD Substance Code (Name) | Name des Studienprogramms | Referenzen |
|---|---|---|
| * New class of SERD (Proteolysis Targeting Chimera, PROTAC) ** New class of SERD (Selective Estrogen Receptor Covalent Antagonics; SERCA) | ||
| LSZ102 | unbekannt | 53 |
| G1T48 (Rintodestrant) | PRESERVE | 54 , 55 |
| RAD1901 (Elacestrant) | EMERALD | 14 , 56 |
| GDC-9545 (Giredestrant) | …ERA (coopERA, lidERA, perseveERA) | 57 , 58 , 59 |
| SAR439859 (Amcenestrant) | AMEERA | 60 , 61 , 62 |
| AZD9833 (Camizestrant) | SERENA | 63 |
| LY3484356 (Imlunestrant) | EMBER | 64 , 65 , 66 |
| Zn-c5 | unbekannt | 67 |
| D-0502 | unbekannt | 68 |
| ARV-471* | unbekannt | 15 |
| H3B-5942** | unbekannt | 69 |