No.	Recommendations/Statements	GoR	LoE	Sources
8.8. reviewed 2021	Consensus-based recommendation after systematic research Adjuvant therapy following primary surgical therapy should be administered on the basis of the postoperative histological tumor stage as follows: Negative lymph nodes; R0; no risk factors Follow-up Negative lymph nodes; R0; one or two risk factors (L1, V1, deep stromal invasion, tumor size > 4 cm) Individualized decision Histologically confirmed lymph-node metastases, pelvic (pN1) or R1 or several (≥ 3) simultaneous risk factors (L1, V1, deep stromal invasion, tumor size > 4 cm, as well as grade G3 if two additional risk factors are present) Adjuvant radio(chemo)therapy including lymphatic drainage areas in the histologically identified area (pelvic) Histologically confirmed para-aortic lymph-node metastases (pM1) Extended adjuvant radio(chemo)therapy including lymphatic drainage areas in the histologically identified area (pelvic and para-aortic fields) Distant metastases, M1 (organ metastases, peritoneal carcinosis, ovarian metastases) Systemic chemotherapy; radiotherapy only indicated in case of bleeding problems	EC