8.10. modified 2021 |
Consensus-based recommendation In stage IA1 without any risk factors, treatment must be administered as follows: Surgery:
Lymph-node removal is not indicated.
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If family planning has been completed, or if the patient wishes greater certainty:
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If the patient wishes to have children:
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If there are positive margins in the conization specimen (R1):
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Following successful pregnancy:
Secondary hysterectomy is possible, particularly if there is persistent HPV, abnormal Pap findings, if the patient wishes maximum safety, or if the cervix is
difficult or impossible to assess.
Radio(chemo)therapy:
|
EC |
8.11. new 2021 |
Consensus-based recommendation In stage IA1 with lymphatic infiltration (L1), treatment must be administered as follows: Surgery:
Sentinel lymphadenectomy is indicated.
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If family planning has been completed, or if the patient wishes greater certainty:
-
If the patient wishes to have children:
-
If there are positive margins in the conization specimen (R1):
-
Following successful pregnancy:
Secondary hysterectomy is possible, particularly if there is persistent HPV, abnormal Pap findings, if the patient wishes maximum safety, or if the cervix is
difficult or impossible to assess.
Radio(chemo)therapy:
|
EC |
8.12. modified 2021 |
Consensus-based recommendation In stage IA1 with at least two risk factors, and stage IA2 with up to one risk factor, treatment should be administered as follows: Surgery:
-
If the patient does not wish to have children and if she wants to be particularly safe and has histologically negative lymph nodes (pelvic) after surgical staging with
SNB:
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If the patient wishes to have children and has negative lymph nodes after surgical staging with SNB:
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If there are sentinel lymph nodes affected by tumor, or there are pelvic lymph-node metastases:
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In premenopausal patients:
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If there are macroscopically tumor-affected pelvic and/or para-aortic lymph nodes:
-
After successful pregnancy:
Secondary hysterectomy, particularly when there is persistent HPV infection, Pap abnormalities, if the patient wants greater safety, and if the cervix can only be
assessed to a limited extent or not at all.
Radio(chemo)therapy:
|
EC |
8.13. modified 2021 |
Consensus-based recommendation In stage IA2 with at least two risk factors, treatment should be administered as follows: Surgery (preserving fertility is not possible) with SNB:
-
With negative lymph nodes (pelvic) after surgical staging:
-
If there are sentinel lymph nodes affected by tumor or if there are pelvic lymph-node metastases:
-
In premenopausal patients:
-
If there are macroscopically tumor-affected pelvic and/or para-aortic lymph nodes:
Radio(chemo)therapy:
|
EC |